Osmolality measures the concentration of a solution relative to the fluid inside your cells, and it's one of the more clinically important — and least publicly known — factors in lubricant safety.
The World Health Organization has published reference ranges suggesting lubricants with very high osmolality can draw water out of epithelial cells, potentially increasing tissue irritation and micro-abrasion with repeated use.
Many mainstream lubricants exceed these reference ranges significantly, which isn't necessarily dangerous for occasional use but is worth knowing for anyone using lubricant frequently or with sensitive tissue.
Alongside osmolality, glycerin and added sugars remain a relevant consideration for anyone prone to yeast infections, since these ingredients can promote yeast overgrowth in susceptible individuals.
https://inwonderstate.com/products/100-natural-water-based-lube-hyaluronic/ is a glycerin-free formulation built with hyaluronic acid for added moisture retention.